Invention Grant
- Patent Title: Piperidin-4YL-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists
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Application No.: US15264185Application Date: 2016-09-13
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Publication No.: US09751860B2Publication Date: 2017-09-05
- Inventor: Marcel Frans Leopold De Bruyn , Gregor James MacDonald , Ludo Edmond Josephine Kennis , Xavier Jean Michel Langlois , Frans Alfons Maria Van Den Keybus , Yves Emiel Maria Van Roosbroeck
- Applicant: JANSSEN PHARMACEUTICA NV
- Applicant Address: BE Belgium
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Belgium
- Priority: EP05110028 20051026; EP06100209 20060110; EP06101545 20060210
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/501 ; C07D409/14
Abstract:
The present invention relates to compounds that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds of the invention can be administered to a patient in need thereof to treat or prevent psychosis including, but not limited to, schizophrenia, schizophreniform disorder and schizoaffective disorder. Compounds of the present invention include those encompassed by Formula I.
Public/Granted literature
- US20170022181A1 FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS Public/Granted day:2017-01-26
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