Invention Grant
- Patent Title: Hydroxy containing FXR (NR1H4) modulating compounds
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Application No.: US14971875Application Date: 2015-12-16
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Publication No.: US09751874B2Publication Date: 2017-09-05
- Inventor: Christian Gege , Olaf Kinzel , Claus Kremoser , Aaron C. Schmitt
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Priority: EP14004259 20141217
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14 ; C07D413/12 ; C07D261/08 ; C07D471/04
Abstract:
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
Public/Granted literature
- US20160176861A1 HYDROXY CONTAINING FXR (NR1H4) MODULATING COMPOUNDS Public/Granted day:2016-06-23
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