Invention Grant
- Patent Title: N-aryl unsaturated fused ring tertiary amine compounds, preparation method and anti-tumor applications thereof
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Application No.: US14403750Application Date: 2013-05-30
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Publication No.: US09751884B2Publication Date: 2017-09-05
- Inventor: Lan Xie , Xiaofeng Wang , Kuo-Hsiung Lee
- Applicant: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Applicant Address: CN Beijing
- Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Current Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
- Current Assignee Address: CN Beijing
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: CN201210176454 20120531
- International Application: PCT/CN2013/076457 WO 20130530
- International Announcement: WO2013/178075 WO 20131205
- Main IPC: C07D473/40
- IPC: C07D473/40 ; C07D403/04 ; C07D473/32 ; C07D215/20 ; C07D473/00 ; C07D401/04 ; C07D413/04 ; C07D473/34

Abstract:
The present invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, its preparation method, a pharmaceutical composition comprising the compound, and its use in manufacture of a medicament for treatment of a disease or disorder, wherein R1, R2, R5, R6, X, Y, Q, W, n1 and n2 are defined as those stated in the description.
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