Invention Grant
- Patent Title: Heteroaryl derivatives as CFTR modulators
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Application No.: US15297983Application Date: 2016-10-19
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Publication No.: US09751890B2Publication Date: 2017-09-05
- Inventor: Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07D405/12
- IPC: C07D405/12 ; A61K31/501 ; C07D491/048 ; A61K31/443 ; A61K45/06 ; A61K31/497 ; A61K31/506 ; C07D405/14 ; A61K31/519 ; G01N33/68
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTC”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20170107225A1 HETEROARYL DERIVATIVES AS CFTR MODULATORS Public/Granted day:2017-04-20
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