Invention Grant
- Patent Title: Administration of DKK1 muteins to treat fibrosis
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Application No.: US14438860Application Date: 2013-11-01
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Publication No.: US09751923B2Publication Date: 2017-09-05
- Inventor: Jeremy Duffield , Shuyu Ren , Rashmi Hedge
- Applicant: University of Washington through its Center for Commercialization , Children's Hospital Medical Center
- Applicant Address: US WA Seattle
- Assignee: University of Washington Through Its Center For Commercialization
- Current Assignee: University of Washington Through Its Center For Commercialization
- Current Assignee Address: US WA Seattle
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Michelle Glasky Bergman
- International Application: PCT/US2013/068107 WO 20131101
- International Announcement: WO2014/071211 WO 20140508
- Main IPC: A61K8/64
- IPC: A61K8/64 ; A61K38/17 ; C07K14/435 ; C07K14/47
Abstract:
The present disclosure provides molecules, compositions and methods for treating scarring in organs. The molecules, compositions and methods treat scarring by modulating the WNT, platelet-derived growth factor receptor (PDGFR), transforming growth factor-beta (TGF3) and/or connective-tissue growth factor (CTGF) signaling pathways.
Public/Granted literature
- US20150337021A1 Molecules, Compositions and Methods to Treat Organ Scarring Public/Granted day:2015-11-26
Information query
