Invention Grant
- Patent Title: Hepatitis C virus neutralizing antibodies and methods
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Application No.: US14437593Application Date: 2012-10-26
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Publication No.: US09751931B2Publication Date: 2017-09-05
- Inventor: Marian Elaine Major , Alla Kachko , Galina Vadimovna Kochneva
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services , Federal Budgetary Research Institution State Research Center of Virology and Biotechnology “Vector”
- Applicant Address: US DC Washington RU Novosibirsk
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,Federal Budgetary Research Institution State Research Center of Virology and Biotechnology “Vector”
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,Federal Budgetary Research Institution State Research Center of Virology and Biotechnology “Vector”
- Current Assignee Address: US DC Washington RU Novosibirsk
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2012/062197 WO 20121026
- International Announcement: WO2014/065822 WO 20140501
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61K39/29 ; A61K45/06 ; C07K14/005 ; C12N7/00 ; G01N33/576 ; C12Q1/04 ; A61K39/00
Abstract:
Novel epitope regions on hepatitis C virus E1E2 glycoprotein that induce a neutralizing antibody response in vivo are identified. Cross-neutralizing monoclonal antibodies that bind specifically to the epitopes are disclosed.
Public/Granted literature
- US20150291684A1 HEPATITIS C VIRUS NEUTRALIZING EPITOPES, ANTIBODIES, AND METHODS Public/Granted day:2015-10-15
Information query
