Invention Grant
- Patent Title: Sortase-modified VHH domains and uses thereof
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Application No.: US14394046Application Date: 2013-04-15
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Publication No.: US09751945B2Publication Date: 2017-09-05
- Inventor: Hidde Ploegh , Maximilian Popp , Juanjo Cragnolini
- Applicant: Whitehead Institute for Biomedical Research
- Applicant Address: US MA Cambridge
- Assignee: Whitehead Institute for Biomedical Research
- Current Assignee: Whitehead Institute for Biomedical Research
- Current Assignee Address: US MA Cambridge
- Agency: Morse, Barnes-Brown & Pendleton, P.C.
- Agent Lisa M. Warren, Esq.
- International Application: PCT/US2013/036630 WO 20130415
- International Announcement: WO2013/155526 WO 20131017
- Main IPC: A61K47/48
- IPC: A61K47/48 ; C07K16/46 ; C07K16/28 ; C07K16/10 ; C07K16/44 ; C07K1/13 ; C12N9/50 ; G01N33/58 ; A61K39/00
Abstract:
In some aspects, polypeptides comprising single domain antibodies and methods of identifying single domain antibodies are provided. In some embodiments polypeptides comprising a single domain antibody and a sortase recognition sequence, are provided. In some aspects, products and methods of use in modulating the immune system, e.g., modulating an immune response, are provided.
Public/Granted literature
- US20150086576A1 SORTASE-MODIFIED VHH DOMAINS AND USES THEREOF Public/Granted day:2015-03-26
Information query
