Invention Grant
- Patent Title: Differentiation of human embryonic stem cells
-
Application No.: US13105285Application Date: 2011-05-11
-
Publication No.: US09752125B2Publication Date: 2017-09-05
- Inventor: Jean Xu
- Applicant: Jean Xu
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Lois A. Gianneschi
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/071
Abstract:
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce a population of cells expressing markers characteristic of the pancreatic endoderm lineage, wherein greater than 50% of the cells in the population co-express PDX1 and NKX6.1.
Public/Granted literature
- US20110281355A1 Differentiation of Human Embryonic Stem Cells Public/Granted day:2011-11-17
Information query
