A noise detection device of a display module, including: a storage module, a processing module and an encoding module; the storage module is used to store parallel video data, the processing module is used to transmit the stored parallel video data to the encoding module, the encoding module is used to convert the stored parallel video data into serial video data through encoding and to transmit the converted serial video data to a timing controller of a display module; the processing module is used to receive mini-LVDS data generated by the timing controller based on the converted serial data, and to convert the mini-LVDS data into the parallel video data; the processing module is used to compare the stored parallel video data with the converted parallel video data, and to determine whether the display module is qualified for noise control according to the comparison result.