Invention Grant
- Patent Title: Fine particles coated with lipid membrane
-
Application No.: US12656487Application Date: 2010-02-01
-
Publication No.: US09757344B2Publication Date: 2017-09-12
- Inventor: Yasuki Kato , Masahiro Yamauchi , Hiroko Kusano , Takeshi Iwata , Takaaki Uochi , Shiro Akinaga
- Applicant: Yasuki Kato , Masahiro Yamauchi , Hiroko Kusano , Takeshi Iwata , Takaaki Uochi , Shiro Akinaga
- Applicant Address: JP Tokyo
- Assignee: KYOWA HAKKO KIRIN CO., LTD.
- Current Assignee: KYOWA HAKKO KIRIN CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2000/305065 20001004
- Main IPC: A61K9/19
- IPC: A61K9/19 ; A61K9/64 ; A61K9/51 ; A61K9/14 ; A61K9/127 ; A61K9/50 ; B01J13/12 ; A61K31/7088 ; A61K47/48

Abstract:
A coated fine particle comprisisng: (i) a complex of a drug and a cationic lipid, wherein (a) the drug is a nucleic acid and the complex is obtained by mixing the drug and the cationic lipid in water, wherein the complex has a diameter of 10 nm to 1,000 nm, and (ii) a lipid layer formed of lipid(s), wherein the lipid(s) is selected from phospholipid, glyceroglycolipid, sphingoglycolipid, cholesterol and synthetic lipid, wherein the complex is coated with the lipid layer.
Public/Granted literature
- US20100166847A1 Method for coating fine particles with lipid membrane Public/Granted day:2010-07-01
Information query