A flame mitigation device (26), along with associated systems and methods, is disclosed. More particularly, a flame mitigation device (26) has at least one sensor (25) configured to sense a flame (21), and at least one suppression agent (28) release device configured to release a flame suppression agent into the projected flame path when the flame is sensed. The sensor (25) may sense the flame either directly or indirectly. A flame mitigation system (26) is also disclosed, wherein the system includes an enclosure (22) and at least one pressure release device configured to release a flame from the enclosure. The system (26) may include at least one sensor (25) configured to sense the flame (21), and a device configured to release a suppression agent (28). A method of mitigating a flame in a combustible material system is also disclosed.