Invention Grant
- Patent Title: Sulfamoylbenzamide derivatives as antiviral agents against HBV infection
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Application No.: US14975239Application Date: 2015-12-18
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Publication No.: US09758477B2Publication Date: 2017-09-12
- Inventor: Ju-Tao Guo , Xiaodong Xu , Timothy M. Block
- Applicant: DREXEL UNIVERSITY , BARUCH S. BLUMBERG INSTITUTE
- Applicant Address: US PA Philadelphia US PA Doylestown
- Assignee: Drexel University,Baruch S. Blumberg Institute
- Current Assignee: Drexel University,Baruch S. Blumberg Institute
- Current Assignee Address: US PA Philadelphia US PA Doylestown
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61K31/47 ; A61K31/18 ; C07C311/46 ; A61K31/341 ; C07D281/16 ; C07D295/26 ; C07D213/40 ; C07D307/52 ; C07D307/68 ; C07D211/96 ; C07D223/04 ; A61K31/167 ; A61K31/4406 ; A61K31/4453 ; A61K31/5375 ; A61K31/54 ; A61K31/553 ; A61K31/44 ; A61K31/541 ; A61K31/445 ; A61K31/5377
Abstract:
The present invention provides sulfamoylbenzamide derivatives, and pharmaceutical compositions thereof. In certain embodiments, the compounds and pharmaceutical compositions of the invention inhibit pregenomic RNA encapsidation. In other embodiments, the compounds and pharmaceutical compositions of the invention are useful for treating Hepatitis B virus (HBV) infection.
Public/Granted literature
- US20160101074A1 SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION Public/Granted day:2016-04-14
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