- Patent Title: Antibody for epitope tagging, hybridoma cell line and uses thereof
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Application No.: US14415702Application Date: 2013-06-20
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Publication No.: US09758571B2Publication Date: 2017-09-12
- Inventor: Seong Hee Bhoo , Tae Ryong Hahn , Tae Lim Kim , Joo Won Suh , Seung Hwan Yang
- Applicant: University-Industry Cooperation Group of Kyung Hee University , Myongji University Industry and Academia Cooperation Foundation
- Applicant Address: KR Yongin-si KR Yongin-si
- Assignee: University—Industry Cooperation Group Of Kyung Hee University,Myongji University Industry and Academia Cooperation Foundation
- Current Assignee: University—Industry Cooperation Group Of Kyung Hee University,Myongji University Industry and Academia Cooperation Foundation
- Current Assignee Address: KR Yongin-si KR Yongin-si
- Agency: The Webb Law Firm
- Priority: KR10-2012-0079615 20120720; KR10-2012-0124733 20121106
- International Application: PCT/KR2013/005433 WO 20130620
- International Announcement: WO2014/014207 WO 20140123
- Main IPC: G01N33/68
- IPC: G01N33/68 ; C07K14/195 ; C12N5/16 ; C07K16/12

Abstract:
There are provided peptide tags derived from bacteriophytochrome (BphP) that is photoreceptor protein of Deinococcus radiodurans, an antibody capable of specifically recognizing the peptide tags, hybridoma cell lines capable of producing the antibody, and uses thereof. The novel peptide tag has advantages in that it has a short length and can remove a non-specific reaction of the conventional c-myc tag and FLAG tag. Therefore, in the case of using the novel peptide tag and antibody thereto, the fusion protein expressed in a recombinant cell can be very effectively detected or purified. In addition, an epitope tagging system including the novel peptide tag and antibody thereto can be applied in various fields such as a determination of an intracellular site, a confirmation of functionality, detection and purification of specific protein, and researches on interaction between proteins.
Public/Granted literature
- US20150191532A1 Antibody For Epitope Tagging, Hybridoma Cell Line and Uses Thereof Public/Granted day:2015-07-09
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