Invention Grant
- Patent Title: Compositions and methods for targeting type 1 interferon producing cells
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Application No.: US14617882Application Date: 2015-02-09
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Publication No.: US09758585B2Publication Date: 2017-09-12
- Inventor: Gino Luigi Vairo , Andrew Nash , Eugene Maraskovsky , Nick Wilson , Samantha Busfield , Con Panousis
- Applicant: CSL Limited
- Applicant Address: AU Parkville
- Assignee: CSL Limited
- Current Assignee: CSL Limited
- Current Assignee Address: AU Parkville
- Agency: Cooley LLP
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61K39/395 ; C07K16/28 ; A61K38/17 ; A61K38/20 ; A61K51/10 ; C07K16/18 ; A61K39/00
Abstract:
The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.
Public/Granted literature
- US20150147322A1 COMPOSITIONS AND METHODS FOR TARGETING TYPE 1 INTERFERON PRODUCING CELLS Public/Granted day:2015-05-28
Information query
