A protective enclosure is provided for securing portable electronic devices within the enclosure. The enclosure generally includes a front structure, a back structure, and at least one bracket. The front structure defines at least one aperture for permitting access to a display of the computing device. The back structure is configured to couple to the front structure. The front structure and back structure are configured to cooperate to substantially enclose at least four corners of the portable computing device. The at least one bracket is configured to engage the front and back structures, and includes a tamper-resistant fastener configured to secure the front and back structures together on the portable computing device.