Systems and methods are disclosed for detecting one or more predefined signals while suppressing interference. In some embodiments, a method of operation of a wireless device in a wireless network to detect a predetermined signal in the presence of interference comprises detecting one or more first cells and detecting one or more predetermined signals from a second cell while spatially filtering transmissions from one or more perceived directions of the one or more first cells, respectively. In this manner, detection of the one or more predefined signals from the second cell is improved. In some embodiments, the one or more first cells are strong relative to the weaker second cell.