Invention Grant
- Patent Title: Rice bran-lipids based formulation and process for preparation thereof for selective delivery of genes to cancer cells
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Application No.: US14406895Application Date: 2013-06-11
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Publication No.: US09763881B2Publication Date: 2017-09-19
- Inventor: Sayantani Roy , Rajkumar Banerjee , Pradosh Prasad Chakrabarti , Badari Narayana Prasad Rachapudi
- Applicant: Council Of Scientific And Industrial Research
- Applicant Address: IN New Delhi
- Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
- Current Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
- Current Assignee Address: IN New Delhi
- Agency: Brinks Gilson & Lione
- Priority: IN1792/DEL/2012 20120611
- International Application: PCT/IN2013/000368 WO 20130611
- International Announcement: WO2013/186793 WO 20131219
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K38/17 ; A61K38/18 ; A61K38/19 ; A61K38/45 ; A61K38/50 ; A61K47/44 ; A61K47/24 ; A61K48/00
Abstract:
The present invention relates to a formulation in which glycolipids and phospholipids, isolated from rice bran gum samples, were used in conjunction with gene carrying lipids to test its efficacy in delivering genes to cancer cells selectively. This formulation did not mediate efficient delivery of genes to non-cancerous cells, thus, showing potential use of this formulation to deliver anticancer therapeutics to cancer cells without eliciting treatment related toxicity to normal cells.
Public/Granted literature
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