Invention Grant
- Patent Title: Polymyxin derivative and uses thereof
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Application No.: US15000443Application Date: 2016-01-19
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Publication No.: US09763996B2Publication Date: 2017-09-19
- Inventor: Martti Sakari Vaara , Timo Ilmari Vaara
- Applicant: Northern Antibiotics Ltd.
- Applicant Address: FI Espoo
- Assignee: Northern Antibiotics, Ltd.
- Current Assignee: Northern Antibiotics, Ltd.
- Current Assignee Address: FI Espoo
- Agency: Lathrop Gage LLP
- Agent Sean M. Coughlin, Esq.
- Main IPC: A61K38/12
- IPC: A61K38/12 ; C07K7/62 ; A61K45/06 ; A61K38/00
Abstract:
The present invention relates to a polymyxin derivative of formula (I) wherein R1 is Dab R2 is Thr R3 is DThr R4 is Dab R5 is Dab R6 is DPhe R7 is Leu R8 is Abu R9 is Dab; R10 is Thr; and R(FA) is octanoyl; and pharmaceutically acceptable salts thereof. The invention further relates to their use in the treatment of infections caused by Gram-negative bacteria.
Public/Granted literature
- US20160206684A1 POLYMYXIN DERIVATIVES AND USES THEREOF Public/Granted day:2016-07-21
Information query
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