Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use

Invention Grant

US09764039B2 Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use 有权

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Patent Title: Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
Application No.: US14328532

Application Date: 2014-07-10
Publication No.: US09764039B2

Publication Date: 2017-09-19
Inventor: Christopher D. Thanos , Ramesh Baliga , Kalyani Penta , Avinash Gill , Gang Yin , Erik Zimmerman
Applicant: Sutro Biopharma, Inc.
Applicant Address: US CA South San Francisco
Assignee: SUTRO BIOPHARMA, INC.
Current Assignee: SUTRO BIOPHARMA, INC.
Current Assignee Address: US CA South San Francisco
Agency: Squire Patton Boggs (US) LLP
Main IPC: A61K47/48
IPC: A61K47/48 ; C07K16/00 ; C07K16/32 ; A61K39/00

Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use

Abstract:

Provided herein are antibodies comprising multiple non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Public/Granted literature

US20150017187A1 ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE Public/Granted day:2015-01-15

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