Invention Grant
- Patent Title: Methods, systems, and apparatus for reducing the frequency and/or severity of photophobic responses or for modulating circadian cycles
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Application No.: US14338182Application Date: 2014-07-22
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Publication No.: US09764157B2Publication Date: 2017-09-19
- Inventor: Steven M. Blair , Bradley Jay Katz
- Applicant: University of Utah Research Foundation
- Applicant Address: US UT Salt Lake City
- Assignee: University of Utah Research Foundation
- Current Assignee: University of Utah Research Foundation
- Current Assignee Address: US UT Salt Lake City
- Agency: Workman Nydegger
- Main IPC: A61N5/06
- IPC: A61N5/06 ; G02B5/28 ; G02B5/22 ; A61M21/02 ; G02C7/10 ; A61M21/00

Abstract:
An optical filter may reduce the frequency and/or severity of photophobic responses or for modulating circadian cycles by controlling light exposure to cells in the human eye in certain wavelengths, such as 480 nm and 590 nm, and a visual spectral response of the human eye. The optical filter may disrupt the isomerization of melanopsin in the human eye reducing the availability of the active isoform, whereas the attenuation of light weighted across the action potential spectrum of the active isoform attenuates the phototransduction cascade leading to photophobic responses. Embodiments of an optical filter are described. In one embodiment an optical filter may be configured to transmit less than a first amount of light in certain wavelengths, and to transmit more than a second amount of light weighted across the visual spectral response. Methods of use and methods of manufacturing optical filters are also described.
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