Invention Grant
- Patent Title: Amido compounds as RORγt modulators and uses thereof
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Application No.: US14343410Application Date: 2012-09-10
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Publication No.: US09765063B2Publication Date: 2017-09-19
- Inventor: Dan Littman , Jun R. Huh , Ruili Huang , Wenwei Huang , Erika E. Englund
- Applicant: Dan Littman , Jun R. Huh , Ruili Huang , Wenwei Huang , Erika E. Englund
- Applicant Address: US NY New York US DC Washington
- Assignee: New York University,The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee: New York University,The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US NY New York US DC Washington
- Agency: Klauber & Jackson LLC
- International Application: PCT/US2012/054424 WO 20120910
- International Announcement: WO2013/036912 WO 20130314
- Main IPC: C07D409/06
- IPC: C07D409/06 ; C07D209/44 ; C07D211/14 ; C07D213/58 ; C07D333/24 ; C07D401/06 ; C07D405/14 ; A61K31/40 ; A61K31/4025 ; A61K31/445 ; A61K31/4709 ; A61K31/495 ; A61K31/496 ; A61K31/5375 ; A61K31/5377

Abstract:
Amido compounds are disclosed that have a formula represented by the following: and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
Public/Granted literature
- US20150057278A1 AMIDO COMPOUNDS AS RORyT MODULATORS AND USES THEREOF Public/Granted day:2015-02-26
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