Invention Grant
- Patent Title: Thiophen-2-yl-pyridin-2-yl-1H-pyrazole-4-carboxylic acid derivatives and the use thereof as soluble guanylate cyclase activators
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Application No.: US15320813Application Date: 2015-07-02
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Publication No.: US09765067B2Publication Date: 2017-09-19
- Inventor: Christopher M. Adams , David B. Belanger , Doug Bevan , Takeru Ehara , Luciana Ferrara , Nan Ji , Donglei Liu , Erik Meredith , Muneto Mogi , James Powers , Ganesh Prasanna , Mitsunori Kato
- Applicant: Christopher M. Adams , David B. Belanger , Doug Bevan , Takeru Ehara , Luciana Ferrara , Nan Ji , Donglei Liu , Erik Meredith , Muneto Mogi , James Powers , Ganesh Prasanna , Mitsunori Kato
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Shawn D. Britt
- International Application: PCT/IB2015/055007 WO 20150702
- International Announcement: WO2016/001876 WO 20160107
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; A61K31/4725 ; A61K31/4439 ; C07D409/14 ; A61K9/00
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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