Invention Grant
- Patent Title: 1H-1,8-naphthyridin-2ones as anti proliferative compounds
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Application No.: US15316832Application Date: 2014-12-15
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Publication No.: US09765072B2Publication Date: 2017-09-19
- Inventor: Amala Kompella , Venugopala Krishna Gampa , Srinivasulu Ganganamoni , Balakrishna Reddy Sirigireddy , Kali Satya Bhujanga Rao Adibhatla , Venkaiah Chowdary Nannapaneni
- Applicant: NATCO PHARMA LIMITED
- Applicant Address: US IN Hyderabad
- Assignee: NATCO PHARMA LIMITED
- Current Assignee: NATCO PHARMA LIMITED
- Current Assignee Address: US IN Hyderabad
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: IN2781/CHE/2014 20140606
- International Application: PCT/IN2014/000777 WO 20141215
- International Announcement: WO2015/186137 WO 20151210
- Main IPC: C07D471/04
- IPC: C07D471/04
Abstract:
The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.
Public/Granted literature
- US20170114057A1 1H-1,8-NAPHTHYRIDIN-2ONES AS ANTI PROLIFERATIVE COMPOUNDS Public/Granted day:2017-04-27
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