Invention Grant
- Patent Title: Synthesis of duocarmycin analogues
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Application No.: US14725252Application Date: 2015-05-29
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Publication No.: US09765077B2Publication Date: 2017-09-19
- Inventor: Michael J Stephenson , Lesley A Howell , Mark Searcey
- Applicant: University of East Anglia
- Applicant Address: GB Norwich
- Assignee: University of East Anglia
- Current Assignee: University of East Anglia
- Current Assignee Address: GB Norwich
- Agency: AGG Intellectual Property Law
- Agent Antoinette G. Giugliano
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04
Abstract:
A novel Fmoc protected duocarmycin subunit and utilization as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents.
Public/Granted literature
- US20160347753A1 Synthesis of Duocarmycin Analogues Public/Granted day:2016-12-01
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