Invention Grant
- Patent Title: Array of micromolded structures for sorting adherent cells
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Application No.: US14714620Application Date: 2015-05-18
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Publication No.: US09765291B2Publication Date: 2017-09-19
- Inventor: Nancy Allbritton , Christopher Sims , Yuli Wang , Pavak Kirit Shah
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Moore & Van Allen PLLC
- Agent Michael G. Johnston
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12M1/32 ; C12M1/12 ; B01J19/00 ; C12M1/00

Abstract:
An apparatus for collecting or culturing cells or cell colonies includes: a common substrate formed from a flexible resilient polymeric material and having a plurality of wells formed therein; and a plurality of rigid cell carriers releasably connected to said common substrate, with said carriers arranged in the form of an array, and with each of the carriers resiliently received in one of the wells. A method of collecting or culturing cells or cell colonies with such an apparatus is carried out by depositing a liquid media carrying cells on the apparatus so that said cells settle on or adhere to said the carriers; and then (c) releasing at least one selected carrier having said cells thereon by gradual application of release energy to each carrier from the cavity in which it is received (e.g., by pushing with a probe).
Public/Granted literature
- US20150251151A1 ARRAY OF MICROMOLDED STRUCTURES FOR SORTING ADHERENT CELLS Public/Granted day:2015-09-10
Information query
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