Invention Grant
- Patent Title: Linear donor constructs for targeted integration
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Application No.: US15146276Application Date: 2016-05-04
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Publication No.: US09765360B2Publication Date: 2017-09-19
- Inventor: Russell DeKelver , Philip D. Gregory , Michael C. Holmes , Fyodor Urnov
- Applicant: Sangamo BioSciences, Inc.
- Applicant Address: US CA Richmond
- Assignee: Sangamo Therapeutics, Inc.
- Current Assignee: Sangamo Therapeutics, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law
- Agent Susan Abrahamson
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/87 ; C07H21/02 ; C07H21/04 ; C12N15/90 ; C12N15/82 ; C12N15/63
Abstract:
Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
Public/Granted literature
- US20160237457A1 LINEAR DONOR CONSTRUCTS FOR TARGETED INTEGRATION Public/Granted day:2016-08-18
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