Invention Grant
- Patent Title: Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
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Application No.: US14991512Application Date: 2016-01-08
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Publication No.: US09765365B2Publication Date: 2017-09-19
- Inventor: Larry Cameron Anthony , Lori Ann Maggio-Hall
- Applicant: BUTAMAX ADVANCED BIOFUELS LLC
- Applicant Address: US DE Wilmington
- Assignee: Butamax Advanced Biofuels LLC
- Current Assignee: Butamax Advanced Biofuels LLC
- Current Assignee Address: US DE Wilmington
- Main IPC: C12P7/16
- IPC: C12P7/16 ; C12N1/20 ; C12N1/00 ; C12N1/12 ; C07H21/04 ; C12N9/04 ; C12N9/10 ; C12N9/88 ; C12N15/52 ; C12P7/18 ; C12P7/26 ; C12P7/64

Abstract:
The invention relates to recombinant host cells having at least one integrated polynucleotide encoding a polypeptide that catalyzes a step in a pyruvate-utilizing biosynthetic pathway, e.g., pyruvate to acetolactate conversion. The invention also relates to methods of increasing the biosynthetic production of isobutanol, 2,3-butanediol, 2-butanol or 2-butanone using such host cells.
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