Systems and methods are disclosed for dynamic addressing of optical fiber sensors in fiber optic interferometry systems. Events that occur along the optical fiber span have defining attributes such as location along the optical fiber span, type, magnitude, time of occurrence, and duration. The event attributes may be used to dynamically form a unique address that fully defines and identifies the event. Other information, such as the corresponding identifier for one or more of the optical fiber span and the corresponding fiber optic interrogator may be included as part of the unique address.