A display device and method of driving the same are disclosed. The display device that transmits signals between a system board section and a circuit board section through an interface and uses Panel Self-Refresh (hereinafter, abbreviated as ‘PSR’) to reduce power consumption, the circuit board section comprising a PSR controller that, when a PSR On signal is supplied from the system board section, changes the operating frequency of a gate driver and data driver to a frequency higher than a reference frequency for driving the panel with PSR On, set by the system board section.