A method and apparatus for determining placement of a plurality of antennas of a distributed antenna system for handling MIMO signals includes, at a first location, simulating the communication of a first MIMO signal by a first remote unit over an air interface in an environment and, at a second location, simulating the communication of a second MIMO signal by a second remote unit over an air interface in the environment. The first and second locations are arranged within the environment to provide overlapping signal coverage of both the first MIMO signal and the second MIMO signal at a third location in the environment. Analysis is made of at least an imbalance of received power between the first and second MIMO signals within the environment at a third location in order to determine whether a desired capacity for MIMO communications with the system has been achieved at the third location.