The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A method and an apparatus for grouping a plurality of beams into a plurality of beam groups in a wireless communication system supporting Multi-Input Multi-Output (MIMO) are provided. The method includes determining at least one preferred beam set, based on a channel between a plurality of transmission beams of a Base Station (BS) and a plurality of reception beams of a Mobile Station (MS), transmitting information on the at least one preferred beam set, to the BS, generating information indicating interference that at least one transmission beam of the BS exerts to the MS, based on a preferred reception beam comprised in the at least one preferred beam set, and transmitting the generated interference information to the BS.