Certain aspects involve power management subsystems for a distributed antenna system (“DAS”) or other telecommunication system. The power management subsystem can include a measurement module and an optimization module. The measurement module can monitor a utilization metric for a remote unit in the DAS or other telecommunication system. The power optimization module can determine whether the remote unit is underutilized based on the monitored utilization metric. The power optimization module can configure the remote unit for a low-power operation in response to determining that the remote unit is underutilized.