Invention Grant
- Patent Title: Parenteral carbamazepine formulation
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Application No.: US14051938Application Date: 2013-10-11
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Publication No.: US09770407B2Publication Date: 2017-09-26
- Inventor: James Cloyd , Angela Birnbaum , Ilo Leppik , Stephen D. Collins
- Applicant: Lundbeck Pharmaceuticals LLC
- Applicant Address: US IL Deerfield
- Assignee: LUNDBECK PHARMACEUTICALS LLC
- Current Assignee: LUNDBECK PHARMACEUTICALS LLC
- Current Assignee Address: US IL Deerfield
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/715 ; A01N43/46 ; A01N43/00 ; A61K31/55 ; A61K9/00 ; A61K31/724 ; C08B37/16 ; A61K47/40

Abstract:
The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration.
Public/Granted literature
- US20140080812A1 NOVEL PARENTERAL CARBAMAZEPINE FORMULATION Public/Granted day:2014-03-20
Information query
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