Invention Grant
- Patent Title: Sulfoximine substituted 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives and their use as CDK9 kinase inhibitors
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Application No.: US14903364Application Date: 2014-07-03
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Publication No.: US09770445B2Publication Date: 2017-09-26
- Inventor: Dirk Kosemund , Ulrich Lücking , Arne Scholz , Gerhard Siemeister , Philip Alexander Lienau
- Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
- Applicant Address: DE Berlin
- Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee: Bayer Pharma Aktiengesellschaft
- Current Assignee Address: DE Berlin
- Agency: Morrison & Foerster LLP
- Priority: EP13175067 20130704
- International Application: PCT/EP2014/064184 WO 20140703
- International Announcement: WO2015/001021 WO 20150108
- Main IPC: A61K31/444
- IPC: A61K31/444 ; C07D405/14 ; C07D401/14

Abstract:
The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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