• Patent Title: Ultrasound contact fluid
  • Application No.: US14398871
    Application Date: 2013-05-08
  • Publication No.: US09770521B2
    Publication Date: 2017-09-26
  • Inventor: Tormod SelbekkGeirmund Unsgård
  • Applicant: Sinvent AS
  • Applicant Address: NO Trondheim
  • Assignee: Sinvent AS
  • Current Assignee: Sinvent AS
  • Current Assignee Address: NO Trondheim
  • Agency: Osha Liang LLP
  • Priority: NO20120529 20120509
  • International Application: PCT/EP2013/059588 WO 20130508
  • International Announcement: WO2013/167654 WO 20131114
  • Main IPC: A61K49/22
  • IPC: A61K49/22 A61B8/08
Ultrasound contact fluid
Abstract:
An aqueous ultrasound contact fluid includes a pharmaceutical grade triglyceride and a pharmaceutically acceptable emulsifier and the use of the ultrasound contact fluid in an intraoperative or interventional ultrasound imaging procedure. A method for intraoperative ultrasound imaging includes filling an aqueous ultrasound contact fluid into a body cavity. The aqueous ultrasound contact fluid is a composition comprising a pharmaceutical grade triglyceride and a pharmaceutically acceptable emulsifier and optionally a pharmaceutically acceptable humectant, and the triglyceride content is in the range of 8-240 g/1000 ml composition contact fluid and the amount of emulsifier is 0.4-18 g/1000 ml composition contact fluid, and optionally a humectant in the amount of 1.2-30 g/1000 ml. The method further includes obtaining an ultrasound image of a body region that comprises at least part of the body cavity filled with the aqueous ultrasound contact fluid. The aqueous ultrasound contact fluid reduces image artifacts associated with the body cavity.
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