Invention Grant
- Patent Title: Neprilysin inhibitors
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Application No.: US15289356Application Date: 2016-10-10
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Publication No.: US09771337B2Publication Date: 2017-09-26
- Inventor: Melissa Fleury , Roland Gendron , Adam D. Hughes , Jane Schmidt
- Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
- Applicant Address: US CA South San Francisco
- Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee: Theravance Biopharma R&D IP, LLC
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah; Wendy Petka
- Main IPC: A61K31/42
- IPC: A61K31/42 ; C07D261/18 ; A61K45/06 ; A61K47/48 ; A61K31/437 ; A61K31/4355 ; A01N47/16 ; C09K15/30 ; C07D213/81 ; C07D237/04 ; A61K31/4196

Abstract:
In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
Public/Granted literature
- US20170088526A1 NEPRILYSIN INHIBITORS Public/Granted day:2017-03-30
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