Invention Grant
- Patent Title: Kinase inhibitors based upon N-alkyl pyrazoles
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Application No.: US14781844Application Date: 2014-04-01
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Publication No.: US09771353B2Publication Date: 2017-09-26
- Inventor: Matthew Colin Thor Fyfe
- Applicant: RESPIVERT LIMITED , TOPIVERT PHARMA LIMITED
- Applicant Address: GB London GB High Wycombe, Buckinghamshire
- Assignee: TOPIVERT PHARMA LIMITED,RESPIVERT LIMITED
- Current Assignee: TOPIVERT PHARMA LIMITED,RESPIVERT LIMITED
- Current Assignee Address: GB London GB High Wycombe, Buckinghamshire
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: GB1305946.4 20130402; GB1322681.6 20131220
- International Application: PCT/GB2014/051017 WO 20140401
- International Announcement: WO2014/162121 WO 20141009
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12 ; C07D403/14 ; A61K31/4439 ; A61K31/506 ; A61K31/5377

Abstract:
Compounds are of formula (I): The compounds have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
Public/Granted literature
- US20160039797A1 KINASE INHIBITORS BASED UPON N-ALKYL PYRAZOLES Public/Granted day:2016-02-11
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