Invention Grant
![Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors](/docs/US/2017-09-26/US09771366B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors
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Application No.: US15436587Application Date: 2017-02-17
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Publication No.: US09771366B2Publication Date: 2017-09-26
- Inventor: Sandra E. Dunn , Aarthi Jayanthan , Jaipal Reddy Nagireddy , Subhash Annedi , John H. Van Drie , Timothy S. Daynard , My-my Huynh
- Applicant: Phoenix Molecular Designs
- Applicant Address: CA British Columbia
- Assignee: PHOENIX MOLECULAR DESIGN
- Current Assignee: PHOENIX MOLECULAR DESIGN
- Current Assignee Address: CA British Columbia
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D487/04 ; C07D471/14 ; A61K45/06
![Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors](/abs-image/US/2017/09/26/US09771366B2/abs.jpg.150x150.jpg)
Abstract:
Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
Public/Granted literature
- US20170240549A1 TETRAHYDROPYRIDO[3',2':4,5]PYRROLO[1,2-a]PYRAZINE-2-CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS Public/Granted day:2017-08-24
Information query
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