Invention Grant
- Patent Title: CD47 targeted therapies for the treatment of infectious disease
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Application No.: US14763758Application Date: 2014-02-05
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Publication No.: US09771428B2Publication Date: 2017-09-26
- Inventor: Kipp Andrew Weiskopf , Kim J. Hasenkrug , Cheryl A. Stoddart , Joseph M. McCune , Irving L. Weissman
- Applicant: The Board of Trustees of the Leland Stanford Junior University , The United States of America, as represented by the Secretary, Department of Health and Human Services , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Stanford US CA Oakland US DC Washington
- Assignee: The Board of Trustees of the Leland Stanford Junior University,The Regents of the University of California,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University,The Regents of the University of California,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US CA Stanford US CA Oakland US DC Washington
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- International Application: PCT/US2014/014905 WO 20140205
- International Announcement: WO2014/124028 WO 20140814
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K16/28 ; A61K39/00
Abstract:
Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRPα on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
Public/Granted literature
- US20150376288A1 CD47 Targeted Therapies for the Treatment of Infectious Disease Public/Granted day:2015-12-31
Information query
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