Invention Grant
- Patent Title: Apparatus for continuous directed evolution of proteins and nucleic acids
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Application No.: US14704226Application Date: 2015-05-05
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Publication No.: US09771574B2Publication Date: 2017-09-26
- Inventor: David R. Liu , Kevin Michael Esvelt
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N15/10
- IPC: C12N15/10 ; C12N7/00
Abstract:
Aspects of the disclosure relate to an apparatus for continuous directed evolution of a gene of interest. In some embodiments, the apparatus comprises a cellstat and a turbidostat. In some embodiments, the apparatus is useful in methods of passing a nucleic acid from cell to cell in a desired function-dependent manner.
Public/Granted literature
- US20150275202A1 CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS Public/Granted day:2015-10-01
Information query
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