Systems and methods for performing personalized operations of a mobile device are provided. An example method includes determining a user-defined signature has been received. The user-defined signature can include a combination of an acoustic input and non-acoustic input. The method can further include performing, in response to the determination, operations of the mobile device, the operations being associated with the user-defined signature. Exemplary acoustic input includes a voice sound with at least one spoken keyword. The spoken keyword is used to identify the operations. Exemplary non-acoustic input includes motions of the mobile device detected by an accelerometer, a gyroscope, and a magnetometer. Exemplary motions include vibrations of the mobile device, tapping the mobile device, rotations of the mobile device, movements of the mobile device as to draw a figure in a space.