Invention Grant
- Patent Title: Small molecule inhibitors of viral protein interactions with human t-RNA
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Application No.: US14419711Application Date: 2013-08-06
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Publication No.: US09775835B2Publication Date: 2017-10-03
- Inventor: Franck Vendeix , Paul F. Agris
- Applicant: Sirga Advanced Biopharma, Inc.
- Applicant Address: US NC Research Triangle Park
- Assignee: Sirga Advanced Biopharma, Inc.
- Current Assignee: Sirga Advanced Biopharma, Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Agris & von Natzmer, LLP
- Agent Cheryl H. Agris
- International Application: PCT/US2013/053747 WO 20130806
- International Announcement: WO2014/025749 WO 20140213
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/445 ; A61K31/085 ; A61K31/136 ; A61K31/18 ; A61K31/222 ; A61K31/37 ; A61K31/427 ; A61K31/428 ; A61K31/4453 ; A61K31/4468 ; A61K31/47 ; A61K31/473 ; A61K31/4745 ; A61K31/519 ; A61K31/53 ; A61K31/63 ; A61K31/517 ; A61K31/5377 ; A61K31/55
Abstract:
Disclosed herein are compounds, compositions and methods of their use to treat HIV/AIDS disease in a subject in need thereof, wherein the compositions comprise small molecule inhibitors that inhibit viral preparation or viral recruitment of human tRNA3Lys.
Public/Granted literature
- US20150190384A1 SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA Public/Granted day:2015-07-09
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