Prodrugs activated by caspase

Invention Grant

US09775914B2 Prodrugs activated by caspase 有权

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Patent Title: Prodrugs activated by caspase
Application No.: US14796219

Application Date: 2015-07-10
Publication No.: US09775914B2

Publication Date: 2017-10-03
Inventor: Sang-Yoon Kim , Youngro Byun , Seung Woo Chung
Applicant: PHAROSGEN CO., LTD.
Applicant Address: KR Seoul
Assignee: PHAROSGEN CO., LTD.
Current Assignee: PHAROSGEN CO., LTD.
Current Assignee Address: KR Seoul
Agency: Foley & Lardner LLP
Priority: KR10-2014-0162555 20141120
Main IPC: A61K47/48
IPC: A61K47/48 ; A61K31/65 ; A61K31/337 ; A61K45/06 ; A61N1/40 ; A61K38/14 ; A61B18/02 ; A61N7/00 ; A61N5/067 ; A61N5/06 ; A61N7/02

Abstract:

Described are prodrug conjugates that release a chemotherapeutic agent upon activation by caspase, and methods using such prodrug conjugates to induce apoptosis, amplify apoptosis, and treat cancer.

Public/Granted literature

US20160144050A1 PRODRUGS ACTIVATED BY CASPASE Public/Granted day:2016-05-26

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