Invention Grant
- Patent Title: Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes
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Application No.: US14892044Application Date: 2014-05-21
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Publication No.: US09777034B2Publication Date: 2017-10-03
- Inventor: Virgil Percec
- Applicant: The Trustees of The University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2014/038926 WO 20140521
- International Announcement: WO2014/190024 WO 20141127
- Main IPC: C07H15/26
- IPC: C07H15/26 ; C07H17/02 ; C07H1/00

Abstract:
The invention concerns compounds of the formula (I) wherein: Y1 and Y2 are independently a monosaccharide or disaccharide; X1 and X2 are independently —(R9—O)m—, —(R10)p—, —O—(R11—O)q—, —R16—O—R17—O— or a covalent bond; Q1 and Q2 are independently a nitrogen-containing heterocycle moiety; Z1 and Z2 are independently —(O—R7)—, —(O—C(═O)—R8)a-, —O—C(═O)—R12—C(=0)-R13—, —O—C(═O)—R14—C(═O)—R15 or a covalent bond; R7-R17 are each independently C1-C6 alkyl; R1-R6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.
Public/Granted literature
- US20160108076A1 MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES Public/Granted day:2016-04-21
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