An integrated ambient sound-isolating pillow composed of comfortable material such as memory foam may be configured as a one-piece pillow for long term resting (e.g. overnight sleeping) use. A one-piece ambient sound-isolating pillow may include a head cradling portion that provides comfortable support for a person's head while cradling at least the sides of the person's head so that a sound-isolating portion of the pillow acts as an ambient sound shield to the person's ears.