An instrument (2) for manipulating an implant is disclosed, the instrument (2) comprising an attachment element (22), which is operable to engage an implant, an actuation rod (20), a distal end (34) of which is connected to the attachment element (22) and a handle (4) having a gripping surface (6). At least a proximal end (32) of the actuation rod (20) is moveably received within the handle (4). The instrument further comprises a drive mechanism (42), mounted on the handle (4) and operable to drive relative movement between the actuation rod (20) and the handle (4). Also disclosed is an instrument (2) for manipulating an implant, the instrument (2) comprising a handle (4), a suction cup (22) operable to engage a surface of an implant and moveably mounted with respect to the handle (4), and a release cord (104), fixedly connected between an edge (88) of the suction cup (22) and the handle (4). A method of releasing an implant from an instrument (2) to which it is attached is also disclosed. The method comprises displacing the suction cup (22) and associated implant with respect to the handle (4) until the release cord (104) causes peel back of the edge (88) of the suction cup (22).