Invention Grant
- Patent Title: Solid ambroxol-containing preparation
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Application No.: US14006183Application Date: 2012-03-15
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Publication No.: US09782365B2Publication Date: 2017-10-10
- Inventor: Rolf-Stefan Brickl , Herrad-Odilia Krenkel
- Applicant: Rolf-Stefan Brickl , Herrad-Odilia Krenkel
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: FR Paris
- Agency: Edell, Shapiro & Finnan, LLC
- Priority: EP11159031 20110321
- International Application: PCT/EP2012/054615 WO 20120315
- International Announcement: WO2012/126813 WO 20120927
- Main IPC: A61K31/137
- IPC: A61K31/137 ; A61K9/16

Abstract:
The present invention relates to solid preparations containing ambroxol which are obtainable by melt extrusion of the mixture consisting of a) 30 to 80% by weight of ambroxol hydrochloride, b) 2 to 68% by weight of at least one hydrogenated vegetable oil, c) 2 to 68% by weight of at least one mixture containing fatty acid ester and/or hydroxy fatty acid ester and d) 0 to 66% by weight of one or more pharmaceutical adjuvants, based in each case on the total amount of the preparation and its use for secretolytic treatment in acute and chronic bronchopulmonary diseases.
Public/Granted literature
- US20140094523A1 SOLID AMBROXOL-CONTAINING PREPARATION Public/Granted day:2014-04-03
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