Invention Grant
- Patent Title: Method for synthesis of an output including diesters of 5-methyl-2-furoic acid
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Application No.: US14661139Application Date: 2015-03-18
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Publication No.: US09783517B2Publication Date: 2017-10-10
- Inventor: Aviad Cahana , Tim Martin
- Applicant: Aviad Cahana , Tim Martin
- Applicant Address: US NM Albuquerque
- Assignee: XF Technologies Inc.
- Current Assignee: XF Technologies Inc.
- Current Assignee Address: US NM Albuquerque
- Agent V. Gerald Grafe
- Main IPC: C07D307/68
- IPC: C07D307/68 ; C07D307/48 ; C07D307/50

Abstract:
The present invention describes methods and apparatuses for the synthesis of 5-(chloromethyl)-2-furaldehyde (CMF) from saccharides in pure or crude form, the method comprising: (a) continuously contacting saccharides in pure or crude form, hydrochloric acid, and an organic solvent, by way of a continuous, biphasic-flow reactor assembly at a temperature from about 60 degrees C. to about 200 degrees C. and pressures from about 1 atmosphere to about 20 atmospheres, such that CMF is produced; (b) separating 5-(chloromethyl)-2-furaldehyde by liquid/liquid and solid/liquid phase separation; (c) producing at least five kilograms per day with at least 50% yield. Embodiments of the present invention can produce CMF in a continuous fashion, with high yield and without degradation of CMF to such side products as 5-(hydroxymethyl)furfural (HMF), 2-(2-hydroxyacetyl)furan (HAF) and levulinic acid (LA).
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