Invention Grant
- Patent Title: Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
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Application No.: US15105411Application Date: 2014-12-15
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Publication No.: US09783531B2Publication Date: 2017-10-10
- Inventor: Michelle R. Machacek , Eric T. Romeo , Alan B. Northrup , Michael D. Altman
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Catherine D. Fitch
- International Application: PCT/US2014/070239 WO 20141215
- International Announcement: WO2015/094997 WO 20150625
- Main IPC: C07D417/12
- IPC: C07D417/12 ; A61K45/06 ; A61K31/427 ; A61K31/433 ; A61K31/5377
Abstract:
The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R3, R5, R6, A, Cy and the subscripts r, s, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
Public/Granted literature
- US20160311813A1 THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS Public/Granted day:2016-10-27
Information query
