Invention Grant
- Patent Title: 5′-nucleotidase inhibitors and therapeutic uses thereof
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Application No.: US15023911Application Date: 2014-09-29
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Publication No.: US09783541B2Publication Date: 2017-10-10
- Inventor: Laurent Chaloin , Suzanne Peyrottes , Corinne Lionne , Zsuzsanna Marton , David Egron , Remi Guillon , Christian Perigaud , Charles Dumontet , Lars Petter Jordheim , Isabelle Krimm
- Applicant: Centre National de la Recherche Scientifique-CNRS , Hospices Civils de Lyon , Ecole Normale Superieure de Lyon , Universite Claude Bernard Lyon 1 , Universite de Montpellier 1
- Applicant Address: FR Paris FR Lyon FR Lyon FR Villeurbanne FR Montpellier
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS,HOSPICES CIVILS DE LYON,ECOLE NORMALE SUPERIEURE DE LYON,UNIVERSITE CLAUDE BERNARD LYON 1,UNIVERSITE DE MONTPELLIER 1
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS,HOSPICES CIVILS DE LYON,ECOLE NORMALE SUPERIEURE DE LYON,UNIVERSITE CLAUDE BERNARD LYON 1,UNIVERSITE DE MONTPELLIER 1
- Current Assignee Address: FR Paris FR Lyon FR Lyon FR Villeurbanne FR Montpellier
- Agency: McAndrews, Held & Malloy, Ltd.
- Priority: FR1359472 20131001
- International Application: PCT/FR2014/052447 WO 20140929
- International Announcement: WO2015/049447 WO 20150409
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07D473/34 ; A61K45/06 ; A61K31/52 ; A61K31/675 ; A61K31/7076 ; C07F9/6561 ; A61K31/7064 ; A61K31/706 ; A61K31/7068 ; A61K31/7072 ; A61K31/708
Abstract:
The subject matter of the present invention is compounds which have a 6-aminopurine backbone corresponding to formula (I): in which R1, R2, R3, X, Y and Z are as defined in any one of claims 1 to 5, and Ar is a biphenyl or a naphthyl which may be substituted with R3, for use in the treatment of cancer.
Public/Granted literature
- US20160272643A1 5'-NUCLEOTIDASE INHIBITORS AND THERAPEUTIC USES THEREOF Public/Granted day:2016-09-22
Information query
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